Study Finds Link Between Exercise and Cancer Prevention

Unlike Estrogen and Progesterone, Irisin is a hormone we seldom hear about in the world of oncology.

Irisin, according to an article from Psychology Today is a hormone released after moderate endurance aerobic activity. It has the ability to help maintain healthy body weight, improve cognition, and slow the aging process. In addition, a study done by the University of New Mexico in Albuquerque showed that Irisin has the ability to reduce breast cancer cell activity.

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The study, published in the International Journal of Cancer’s February issue, involved introducing genetically engineered Irisin to triple negative breast cancer cells. They divided the cells into three groups – Group A, normal cells treated with Irisin; Group B, malignant cells with Irisin and group C malignant cells with Irisin and the chemo drug doxorubicin.  The results were as follows:

  • Irisin had no effect on the cells in Group A.
  • There was a 34% reduction of malignant cells in Group B.
  • The cells absorbed less than normal amounts of Doxorubicin, but there was a greater amount of cancer cell death in Group C as compared to Groups A and B.

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In summary, Irisin has been proven to slow down metastasis and can even be used as an adjunctive to chemotherapy. The results of this study will surely make a big impact on how we treat cancer today, especially on recommending moderate exercise as part of cancer treatment. Irisin may be the missing link between risk reduction and physical activity – the reason why women who exercise are known to decrease their chances of developing breast cancer by up to 40%.

So what do you think ladies? Shall we all take a good long walk today?


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